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Efficient Transgene Reconstitution with Hybrid Dual AAV Vectors Carrying the Minimized Bridging Sequences

A hybrid dual-vector system was developed recently as a universal platform to double the packaging capacity of recombinant adeno-associated virus (AAV). In this system, the expression cassette is split into two independent AAV vectors. A highly recombinogenic bridging DNA sequence is engineered in b...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ghosh, Arkasubhra, Yue, Yongping, Duan, Dongsheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025179/
https://ncbi.nlm.nih.gov/pubmed/20662564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.122
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