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Improved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy
Despite significant advancements with recombinant AAV2 or AAV8 vectors for liver directed gene therapy in humans, it is well-recognized that host and vector-related immune challenges need to be overcome for long-term gene transfer. To overcome these limitations, alternate AAV serotypes (1–10) are be...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652085/ https://ncbi.nlm.nih.gov/pubmed/23665951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01832 |
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