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Activation of the Cellular Unfolded Protein Response by Recombinant Adeno-Associated Virus Vectors

The unfolded protein response (UPR) is a stress-induced cyto-protective mechanism elicited towards an influx of large amount of proteins in the endoplasmic reticulum (ER). In the present study, we evaluated if AAV manipulates the UPR pathways during its infection. We first examined the role of the t...

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Hlavní autoři: Balakrishnan, Balaji, Sen, Dwaipayan, Hareendran, Sangeetha, Roshini, Vaani, David, Sachin, Srivastava, Alok, Jayandharan, Giridhara R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540029/
https://ncbi.nlm.nih.gov/pubmed/23320106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053845
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