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Activation of the Cellular Unfolded Protein Response by Recombinant Adeno-Associated Virus Vectors
The unfolded protein response (UPR) is a stress-induced cyto-protective mechanism elicited towards an influx of large amount of proteins in the endoplasmic reticulum (ER). In the present study, we evaluated if AAV manipulates the UPR pathways during its infection. We first examined the role of the t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540029/ https://ncbi.nlm.nih.gov/pubmed/23320106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053845 |
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