Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients

PURPOSE: To evaluate the impact of miR-155 on the outcome of adults with cytogenetically normal (CN) acute myeloid leukemia (AML) in the context of other clinical and molecular prognosticators and to gain insight into the leukemogenic role of this microRNA. PATIENTS AND METHODS: We evaluated 363 pat...

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Hauptverfasser: Marcucci, Guido, Maharry, Kati S., Metzeler, Klaus H., Volinia, Stefano, Wu, Yue-Zhong, Mrózek, Krzysztof, Nicolet, Deedra, Kohlschmidt, Jessica, Whitman, Susan P., Mendler, Jason H., Schwind, Sebastian, Becker, Heiko, Eisfeld, Ann-Kathrin, Carroll, Andrew J., Powell, Bayard L., Kolitz, Jonathan E., Garzon, Ramiro, Caligiuri, Michael A., Stone, Richard M., Bloomfield, Clara D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731981/
https://ncbi.nlm.nih.gov/pubmed/23650424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.45.6228
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