GAS6 expression identifies high-risk adult AML patients: potential implications for therapy

Emerging data demonstrate important roles for the TYRO3/AXL/MERTK receptor tyrosine kinase (TAM RTK) family in diverse cancers. We investigated the prognostic relevance of GAS6 expression, encoding the common TAM RTK ligand, in 270 adults (n=71 aged <60 years; n=199 aged ≥60 years) with de novo c...

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Detalhes bibliográficos
Main Authors: Whitman, Susan P., Kohlschmidt, Jessica, Maharry, Kati, Volinia, Stefano, Mrózek, Krzysztof, Nicolet, Deedra, Schwind, Sebastian, Becker, Heiko, Metzeler, Klaus H., Mendler, Jason H., Eisfeld, Ann-Kathrin, Carroll, Andrew J., Powell, Bayard L., Carter, Thomas H., Baer, Maria R., Kolitz, Jonathan E., Park, Il-Kyoo, Stone, Richard M., Caligiuri, Michael A., Marcucci, Guido, Bloomfield, Clara D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047202/
https://ncbi.nlm.nih.gov/pubmed/24326683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.371
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