Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients

PURPOSE: To evaluate the impact of miR-155 on the outcome of adults with cytogenetically normal (CN) acute myeloid leukemia (AML) in the context of other clinical and molecular prognosticators and to gain insight into the leukemogenic role of this microRNA. PATIENTS AND METHODS: We evaluated 363 pat...

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Autors principals: Marcucci, Guido, Maharry, Kati S., Metzeler, Klaus H., Volinia, Stefano, Wu, Yue-Zhong, Mrózek, Krzysztof, Nicolet, Deedra, Kohlschmidt, Jessica, Whitman, Susan P., Mendler, Jason H., Schwind, Sebastian, Becker, Heiko, Eisfeld, Ann-Kathrin, Carroll, Andrew J., Powell, Bayard L., Kolitz, Jonathan E., Garzon, Ramiro, Caligiuri, Michael A., Stone, Richard M., Bloomfield, Clara D.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2013
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ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731981/
https://ncbi.nlm.nih.gov/pubmed/23650424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.45.6228
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