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Mechanisms regulating resistance to inhibitors of topoisomerase II
Inhibitors of topoisomerase II (topo II) are clinically effective in the management of hematological malignancies and solid tumors. The efficacy of anti-tumor drugs targeting topo II is often limited by resistance and studies with in vitro cell culture models have provided several insights on potent...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729981/ https://ncbi.nlm.nih.gov/pubmed/23914174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00089 |
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