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Conserved Roles of the Prion Protein Domains on Subcellular Localization and Cell-Cell Adhesion
Analyses of cultured cells and transgenic mice expressing prion protein (PrP) deletion mutants have revealed that some properties of PrP -such as its ability to misfold, aggregate and trigger neurotoxicity- are controlled by discrete molecular determinants within its protein domains. Although the co...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729945/ https://ncbi.nlm.nih.gov/pubmed/23936187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070327 |
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