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Regulation of Embryonic Cell Adhesion by the Prion Protein

Prion proteins (PrPs) are key players in fatal neurodegenerative disorders, yet their physiological functions remain unclear, as PrP knockout mice develop rather normally. We report a strong PrP loss-of-function phenotype in zebrafish embryos, characterized by the loss of embryonic cell adhesion and...

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Detalhes bibliográficos
Main Authors: Málaga-Trillo, Edward, Solis, Gonzalo P, Schrock, Yvonne, Geiss, Corinna, Luncz, Lydia, Thomanetz, Venus, Stuermer, Claudia A. O
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653553/
https://ncbi.nlm.nih.gov/pubmed/19278297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000055
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