HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy

The cytogenetically normal subtype of acute myeloid leukemia is associated with an intermediate risk which complicates therapeutic options. Lower overall HOX/TALE expression appears to correlate with more favorable prognosis/better response to treatment in some leukemias and solid cancer. The functi...

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Hlavní autoři: Dickson, Glenda J., Liberante, Fabio G., Kettyle, Laura M, O’Hagan, Kathleen A., Finnegan, Damian P. J., Bullinger, Lars, Geerts, Dirk, McMullin, Mary Frances, Lappin, Terry R. J., Mills, Ken I., Thompson, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2013
Témata:
Original Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729901/
https://ncbi.nlm.nih.gov/pubmed/23539541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.079012
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