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HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy

The cytogenetically normal subtype of acute myeloid leukemia is associated with an intermediate risk which complicates therapeutic options. Lower overall HOX/TALE expression appears to correlate with more favorable prognosis/better response to treatment in some leukemias and solid cancer. The functi...

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書誌詳細
主要な著者: Dickson, Glenda J., Liberante, Fabio G., Kettyle, Laura M, O’Hagan, Kathleen A., Finnegan, Damian P. J., Bullinger, Lars, Geerts, Dirk, McMullin, Mary Frances, Lappin, Terry R. J., Mills, Ken I., Thompson, Alexander
フォーマット: Artigo
言語:Inglês
出版事項: Ferrata Storti Foundation 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729901/
https://ncbi.nlm.nih.gov/pubmed/23539541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.079012
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