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HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy

The cytogenetically normal subtype of acute myeloid leukemia is associated with an intermediate risk which complicates therapeutic options. Lower overall HOX/TALE expression appears to correlate with more favorable prognosis/better response to treatment in some leukemias and solid cancer. The functi...

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Bibliografiset tiedot
Päätekijät: Dickson, Glenda J., Liberante, Fabio G., Kettyle, Laura M, O’Hagan, Kathleen A., Finnegan, Damian P. J., Bullinger, Lars, Geerts, Dirk, McMullin, Mary Frances, Lappin, Terry R. J., Mills, Ken I., Thompson, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ferrata Storti Foundation 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729901/
https://ncbi.nlm.nih.gov/pubmed/23539541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.079012
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