HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy

The cytogenetically normal subtype of acute myeloid leukemia is associated with an intermediate risk which complicates therapeutic options. Lower overall HOX/TALE expression appears to correlate with more favorable prognosis/better response to treatment in some leukemias and solid cancer. The functi...

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Detalhes bibliográficos
Main Authors: Dickson, Glenda J., Liberante, Fabio G., Kettyle, Laura M, O’Hagan, Kathleen A., Finnegan, Damian P. J., Bullinger, Lars, Geerts, Dirk, McMullin, Mary Frances, Lappin, Terry R. J., Mills, Ken I., Thompson, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729901/
https://ncbi.nlm.nih.gov/pubmed/23539541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.079012
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