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Elastin Haploinsufficiency Induces Alternative Aging Processes in the Aorta
Elastin, the main component of elastic fibers, is synthesized only in early life and provides the blood vessels with their elastic properties. With aging, elastin is progressively degraded, leading to arterial enlargement, stiffening, and dysfunction. Also, elastin is a key regulator of vascular smo...
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| 主要な著者: | , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729436/ https://ncbi.nlm.nih.gov/pubmed/18173368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2007.0587 |
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