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The Wonders of Flap Endonucleases: Structure, Function, Mechanism and Regulation
Processing of Okazaki fragments to complete lagging-strand DNA synthesis requires coordination among several proteins. RNA primers and DNA synthesised by DNA polymerase α are displaced by DNA polymerase δ to create bifurcated nucleic acid structures known as 5′-flaps. These 5′-flaps are removed by F...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3728657/ https://ncbi.nlm.nih.gov/pubmed/22918592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-007-4572-8_16 |
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