Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

BACKGROUND: Dysfunction of regulatory T (Treg) cells has been detected in diverse inflammatory disorders, including chronic graft-versus-host disease (GVHD). Interleukin-2 is critical for Treg cell growth, survival, and activity. We hypothesized that low-dose interleukin-2 could preferentially enhan...

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Autors principals: Koreth, John, Matsuoka, Ken-ichi, Kim, Haesook T., McDonough, Sean M., Bindra, Bhavjot, Alyea, Edwin P., Armand, Philippe, Cutler, Corey, Ho, Vincent T., Treister, Nathaniel S., Bienfang, Don C., Prasad, Sashank, Tzachanis, Dmitrios, Joyce, Robin M., Avigan, David E., Antin, Joseph H., Ritz, Jerome, Soiffer, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727432/
https://ncbi.nlm.nih.gov/pubmed/22129252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1108188
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