Low telomerase activity in CD4(+) regulatory T cells in patients with severe chronic GVHD after hematopoietic stem cell transplantation

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Treg) play an important role in the control of chronic graft-versus-host disease (cGVHD). In this study, we examined telomere length and telomerase activity of Treg and conventional CD4(+) T cells (Tcon) in 61 patients who survived more than 2 years after al...

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Hlavní autoři: Kawano, Yutaka, Kim, Haesook T., Matsuoka, Ken-ichi, Bascug, Gregory, McDonough, Sean, Ho, Vincent T., Cutler, Corey, Koreth, John, Alyea, Edwin P., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208307/
https://ncbi.nlm.nih.gov/pubmed/21900196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-362137
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