Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial

B cells are implicated in the pathophysiology of chronic graft-vs-host disease (GVHD), and phase 2 trials suggest that B cell depletion can treat established chronic GVHD. We hypothesized that posttransplantation B cell depletion could prevent the occurrence of chronic GVHD. We performed a 65-patien...

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Detalhes bibliográficos
Main Authors: Cutler, Corey, Kim, Haesook T., Bindra, Bhavjot, Sarantopoulos, Stefanie, Ho, Vincent T., Chen, Yi-Bin, Rosenblatt, Jacalyn, McDonough, Sean, Watanaboonyongcharoen, Phandee, Armand, Philippe, Koreth, John, Glotzbecker, Brett, Alyea, Edwin, Blazar, Bruce R., Soiffer, Robert J., Ritz, Jerome, Antin, Joseph H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750344/
https://ncbi.nlm.nih.gov/pubmed/23861248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-495895
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