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A Phase I Study of Alemtuzumab for Therapy of Steroid-Refractory Chronic Graft-versus-Host Disease

Steroid-refractory chronic graft-versus-host disease (cGvHD) carries a poor prognosis with no agreed-upon algorithm for treatment. Since both B and T cells contribute to the pathophysiology of cGvHD, we conducted a Phase 1 study in subjects with steroid-refractory cGvHD using the anti-CD52 antibody...

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Bibliographic Details
Main Authors: Nikiforow, Sarah, Kim, Haesook T., Bindra, Bhavjot, McDonough, Sean, Glotzbecker, Brett, Armand, Philippe, Koreth, John, Ho, Vincent T., Alyea, Edwin P., Blazar, Bruce R., Ritz, Jerome, Soiffer, Robert J., Antin, Joseph H., Cutler, Corey S.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642980/
https://ncbi.nlm.nih.gov/pubmed/23416855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.02.009
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