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Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease
CD4(+)FoxP3(+) regulatory T cells (Tregs) play a central role in the maintenance of immune tolerance after allogeneic hematopoietic stem cell transplantation. We recently reported that daily administration of low-dose IL-2 induces selective expansion of functional Treg and clinical improvement of ch...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686517/ https://ncbi.nlm.nih.gov/pubmed/23552371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005265 |
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