Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease

CD4(+)FoxP3(+) regulatory T cells (Tregs) play a central role in the maintenance of immune tolerance after allogeneic hematopoietic stem cell transplantation. We recently reported that daily administration of low-dose IL-2 induces selective expansion of functional Treg and clinical improvement of ch...

Full description

Saved in:
Bibliographic Details
Main Authors: Matsuoka, Ken-ichi, Koreth, John, Kim, Haesook T., Bascug, O. Gregory, McDonough, Sean, Kawano, Yutaka, Murase, Kazuyuki, Cutler, Corey, Ho, Vincent T., Alyea, Edwin P., Armand, Philippe, Blazar, Bruce R., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686517/
https://ncbi.nlm.nih.gov/pubmed/23552371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005265
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items