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Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease

CD4(+)FoxP3(+) regulatory T cells (Tregs) play a central role in the maintenance of immune tolerance after allogeneic hematopoietic stem cell transplantation. We recently reported that daily administration of low-dose IL-2 induces selective expansion of functional Treg and clinical improvement of ch...

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書誌詳細
主要な著者: Matsuoka, Ken-ichi, Koreth, John, Kim, Haesook T., Bascug, O. Gregory, McDonough, Sean, Kawano, Yutaka, Murase, Kazuyuki, Cutler, Corey, Ho, Vincent T., Alyea, Edwin P., Armand, Philippe, Blazar, Bruce R., Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686517/
https://ncbi.nlm.nih.gov/pubmed/23552371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005265
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