Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

BACKGROUND: Dysfunction of regulatory T (Treg) cells has been detected in diverse inflammatory disorders, including chronic graft-versus-host disease (GVHD). Interleukin-2 is critical for Treg cell growth, survival, and activity. We hypothesized that low-dose interleukin-2 could preferentially enhan...

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Bibliografiske detaljer
Main Authors: Koreth, John, Matsuoka, Ken-ichi, Kim, Haesook T., McDonough, Sean M., Bindra, Bhavjot, Alyea, Edwin P., Armand, Philippe, Cutler, Corey, Ho, Vincent T., Treister, Nathaniel S., Bienfang, Don C., Prasad, Sashank, Tzachanis, Dmitrios, Joyce, Robin M., Avigan, David E., Antin, Joseph H., Ritz, Jerome, Soiffer, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727432/
https://ncbi.nlm.nih.gov/pubmed/22129252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1108188
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