Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

BACKGROUND: Dysfunction of regulatory T (Treg) cells has been detected in diverse inflammatory disorders, including chronic graft-versus-host disease (GVHD). Interleukin-2 is critical for Treg cell growth, survival, and activity. We hypothesized that low-dose interleukin-2 could preferentially enhan...

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主要な著者: Koreth, John, Matsuoka, Ken-ichi, Kim, Haesook T., McDonough, Sean M., Bindra, Bhavjot, Alyea, Edwin P., Armand, Philippe, Cutler, Corey, Ho, Vincent T., Treister, Nathaniel S., Bienfang, Don C., Prasad, Sashank, Tzachanis, Dmitrios, Joyce, Robin M., Avigan, David E., Antin, Joseph H., Ritz, Jerome, Soiffer, Robert J.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727432/
https://ncbi.nlm.nih.gov/pubmed/22129252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1108188
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