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Saturable Leptin Transport Across the BBB Persists in EAE Mice
We have shown that mice with experimental autoimmune encephalomyelitis (EAE), a model of multiple sclerosis, have upregulated leptin receptor expression in reactive astrocytes of the hippocampus, a region involved in sickness behavior. Leptin can exacerbate EAE when its serum concentration is high....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726568/ https://ncbi.nlm.nih.gov/pubmed/23504255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-013-9993-8 |
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