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Endothelial cell leptin receptor mutant mice have hyperleptinemia and reduced tissue uptake
Hyperleptinemia is usually associated with obesity and leptin resistance. Endothelial cell leptin receptor knockout (ELKO) mice without a signaling membrane-bound leptin receptor in endothelia, however, have profound hyperleptinemia without signs of leptin resistance. Leptin mRNA in adipose tissue w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091723/ https://ncbi.nlm.nih.gov/pubmed/23359322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24325 |
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