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Loss of astrocytic leptin signaling worsens experimental autoimmune encephalomyelitis
Leptin is commonly thought to play a detrimental role in exacerbating experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis. Paradoxically, we show here that astrocytic leptin signaling has beneficial effects in reducing disease severity. In the astrocyte specific leptin receptor kn...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818286/ https://ncbi.nlm.nih.gov/pubmed/23916894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2013.07.176 |
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