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Cerebral interleukin-15 shows upregulation and beneficial effects in experimental autoimmune encephalomyelitis

Interleukin (IL)-15 can cross the blood-brain barrier to act on its specific brain receptor (IL15Rα) and co-receptors. The important roles of neuronal IL15 and IL15Rα in experimental autoimmune encephalomeylitis (EAE) are suggested by the upregulation of IL15Rα mRNA in different regions of the brain...

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Detalhes bibliográficos
Main Authors: Wu, Xiaojun, Pan, Weihong, He, Yi, Hsuchou, Hung, Kastin, Abba J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883030/
https://ncbi.nlm.nih.gov/pubmed/20430449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.04.001
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