Leukocyte infiltration into spinal cord of EAE mice is attenuated by removal of endothelial leptin signaling

Leptin, a pleiotropic adipokine, crosses the blood-brain barrier (BBB) and blood–spinal cord barrier (BSCB) from the periphery and facilitates experimental autoimmune encephalomyelitis (EAE). EAE induces dynamic changes of leptin receptors in enriched brain and spinal cord microvessels, leading to f...

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Main Authors: Ouyang, Suidong, Hsuchou, Hung, Kastin, Abba J., Mishra, Pramod K., Wang, Yuping, Pan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131983/
https://ncbi.nlm.nih.gov/pubmed/24576482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2014.02.003
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