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Endothelial cell leptin receptor mutant mice have hyperleptinemia and reduced tissue uptake

Hyperleptinemia is usually associated with obesity and leptin resistance. Endothelial cell leptin receptor knockout (ELKO) mice without a signaling membrane-bound leptin receptor in endothelia, however, have profound hyperleptinemia without signs of leptin resistance. Leptin mRNA in adipose tissue w...

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Bibliografiset tiedot
Päätekijät: Hsuchou, Hung, Jayaram, Bhavaani, Kastin, Abba J., Wang, Yuping, Ouyang, Suidong, Pan, Weihong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091723/
https://ncbi.nlm.nih.gov/pubmed/23359322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24325
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