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C-Reactive Protein Increases BBB Permeability: Implications for Obesity and Neuroinflammation
BACKGROUND/AIMS: Acute phase C-reactive protein (CRP), elevated in obesity and inflammation, is a major binding protein for leptin. It is thought that CRP contributes to leptin resistance by preventing leptin from crossing the blood-brain barrier (BBB). Here we determined how CRP interacts with the...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4099000/ https://ncbi.nlm.nih.gov/pubmed/23018453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000343302 |
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