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Neuroinflammation activates efflux transport by NFκB: promoter analysis in BBB endothelia
BACKGROUND/AIMS: Although it is known that drug delivery across the blood-brain barrier (BBB) may be hampered by efflux transport activity of the multidrug resistance (mdr) gene product P-glycoprotein, it is not clear how inflammation regulates efflux transporters. In rat brain endothelial (RBE4) ce...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677694/ https://ncbi.nlm.nih.gov/pubmed/19088456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000185558 |
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