The Role of Cerebral Vascular NFκB in LPS-induced Inflammation: Differential Regulation of Efflux Transporter and Transporting Cytokine Receptors

BACKGROUND/AIMS: The transcription factor NFκB is a major mediator of lipopolysaccharide (LPS) signaling. We determined the role of NFκB activation in regulatory changes of the P-glycoprotein (Pgp) drug efflux transporter at the blood-brain barrier (BBB) and proinflammatory cytokine receptors. METHO...

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Main Authors: Pan, Weihong, Yu, Chuanhui, Hsuchou, Hung, Kastin, Abba J.
格式: Artigo
語言:Inglês
出版: S. Karger AG 2010
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Original Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910582/
https://ncbi.nlm.nih.gov/pubmed/20511707
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