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The Role of Cerebral Vascular NFκB in LPS-induced Inflammation: Differential Regulation of Efflux Transporter and Transporting Cytokine Receptors
BACKGROUND/AIMS: The transcription factor NFκB is a major mediator of lipopolysaccharide (LPS) signaling. We determined the role of NFκB activation in regulatory changes of the P-glycoprotein (Pgp) drug efflux transporter at the blood-brain barrier (BBB) and proinflammatory cytokine receptors. METHO...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910582/ https://ncbi.nlm.nih.gov/pubmed/20511707 |
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