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Developmental Changes of Leptin Receptors in Cerebral Microvessels: Unexpected Relation to Leptin Transport

The adipokine leptin participates not only in the regulation of feeding and obesity in adults but also in neonatal development. It crosses the blood-brain barrier (BBB) by receptor-mediated transport. Leptin concentrations in blood differ between neonates and adults. We determined the developmental...

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Detalhes bibliográficos
Main Authors: Pan, Weihong, Hsuchou, Hung, Tu, Hong, Kastin, Abba J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276815/
https://ncbi.nlm.nih.gov/pubmed/18039787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0893
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