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Unique leptin trafficking by a tailless receptor

Impairment in blood-to-brain transport of leptin is a major cause as well as consequence of obesity. Leptin crosses the blood-brain barrier by transcytosis rather than undergoing intracellular degradation. Results from previous studies have indicated that the membrane juxtapositional cytoplasmic seq...

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Detalhes bibliográficos
Main Authors: Tu, Hong, Hsuchou, Hung, Kastin, Abba J., Wu, Xiaojun, Pan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887260/
https://ncbi.nlm.nih.gov/pubmed/20223942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-143487
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