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Unique leptin trafficking by a tailless receptor
Impairment in blood-to-brain transport of leptin is a major cause as well as consequence of obesity. Leptin crosses the blood-brain barrier by transcytosis rather than undergoing intracellular degradation. Results from previous studies have indicated that the membrane juxtapositional cytoplasmic seq...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Federation of American Societies for Experimental Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887260/ https://ncbi.nlm.nih.gov/pubmed/20223942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-143487 |
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