Folliculin Contributes to VHL Tumor Suppressing Activity in Renal Cancer through Regulation of Autophagy

Von Hippel-Lindau tumor suppressor (VHL) is lost in the majority of clear cell renal cell carcinomas (ccRCC). Folliculin (FLCN) is a tumor suppressor whose function is lost in Birt-Hogg-Dubé syndrome (BHD), a disorder characterized by renal cancer of multiple histological types including clear cell...

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Autori principali: Bastola, Prabhat, Stratton, Yiwen, Kellner, Emily, Mikhaylova, Olga, Yi, Ying, Sartor, Maureen A., Medvedovic, Mario, Biesiada, Jacek, Meller, Jarek, Czyzyk-Krzeska, Maria F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726479/
https://ncbi.nlm.nih.gov/pubmed/23922894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070030
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