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Mechanisms of Nrf2 Protection in Astrocytes as Identified by Quantitative Proteomics and siRNA Screening
The Nrf2 (NF-E2 related factor 2)-ARE (antioxidant response element) pathway controls a powerful array of endogenous cellular antioxidant systems and is an important pathway in the detoxification of reactive oxygen species (ROS) in the brain. Using a combination of quantitative proteomics and siRNA...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Public Library of Science
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726381/ https://ncbi.nlm.nih.gov/pubmed/23922950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070163 |
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