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Mechanisms of Nrf2 Protection in Astrocytes as Identified by Quantitative Proteomics and siRNA Screening

The Nrf2 (NF-E2 related factor 2)-ARE (antioxidant response element) pathway controls a powerful array of endogenous cellular antioxidant systems and is an important pathway in the detoxification of reactive oxygen species (ROS) in the brain. Using a combination of quantitative proteomics and siRNA...

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Detalhes bibliográficos
Main Authors: Dowell, James A., Johnson, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726381/
https://ncbi.nlm.nih.gov/pubmed/23922950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070163
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