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Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels
ATP-gated P2X receptors and acid-sensing ion channels are cation-selective, trimeric ligand-gated ion channels unrelated in amino acid sequence. Nevertheless, initial crystal structures of the P2X4 receptor and acid-sensing ion channel 1a in resting/closed and in non conductive/desensitized conforma...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725955/ https://ncbi.nlm.nih.gov/pubmed/23628284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2013.04.005 |
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