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X-ray structure of acid-sensing ion channel 1–snake toxin complex reveals open state of a Na(+)-selective channel
Acid sensing ion channels (ASICs) detect extracellular protons produced during inflammation or ischemic injury and belong to the super family of degenerin/epithelial sodium channels. Here, we determine the cocrystal structure of chicken ASIC1a with MitTx, a pain-inducing toxin from the Texas coral s...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4190031/ https://ncbi.nlm.nih.gov/pubmed/24507937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.01.011 |
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