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Molecular mechanism of ATP binding and ion channel activation in P2X receptors

P2X receptors are trimeric ATP-activated ion channels permeable to Na(+), K(+) and Ca(+2). The seven P2X receptor subtypes are implicated in physiological processes that include modulation of synaptic transmission, contraction of smooth muscle, secretion of chemical transmitters and regulation of im...

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Autors principals: Hattori, Motoyuki, Gouaux, Eric
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391165/
https://ncbi.nlm.nih.gov/pubmed/22535247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11010
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