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Molecular mechanism of ATP binding and ion channel activation in P2X receptors
P2X receptors are trimeric ATP-activated ion channels permeable to Na(+), K(+) and Ca(+2). The seven P2X receptor subtypes are implicated in physiological processes that include modulation of synaptic transmission, contraction of smooth muscle, secretion of chemical transmitters and regulation of im...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391165/ https://ncbi.nlm.nih.gov/pubmed/22535247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11010 |
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