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Crystal structure of the ATP-gated P2X4 ion channel in the closed state

P2X receptors are cation selective ion channels gated by extracellular ATP and implicated in diverse physiological processes, from synaptic transmission to inflammation to the sensing of taste and pain. Because P2X receptors are not related to other ion channel proteins of known structure, there is...

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Detalhes bibliográficos
Main Authors: Kawate, Toshimitsu, Michel, Jennifer Carlisle, Birdsong, William T., Gouaux, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720809/
https://ncbi.nlm.nih.gov/pubmed/19641588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08198
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