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Crystal structure of the ATP-gated P2X4 ion channel in the closed state

P2X receptors are cation selective ion channels gated by extracellular ATP and implicated in diverse physiological processes, from synaptic transmission to inflammation to the sensing of taste and pain. Because P2X receptors are not related to other ion channel proteins of known structure, there is...

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Dettagli Bibliografici
Autori principali: Kawate, Toshimitsu, Michel, Jennifer Carlisle, Birdsong, William T., Gouaux, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720809/
https://ncbi.nlm.nih.gov/pubmed/19641588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08198
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