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Structural plasticity and dynamic selectivity of acid sensing ion channel–toxin complexes

Acid sensing ion channels (ASICs) are voltage-independent, amiloride-sensitive channels implicated in diverse physiological processes ranging from nociception to taste. Despite the importance of ASICs in physiology, we know little about the mechanism of channel activation. Here we show that psalmoto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Baconguis, Isabelle, Gouaux, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725952/
https://ncbi.nlm.nih.gov/pubmed/22842900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11375
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