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Structural plasticity and dynamic selectivity of acid sensing ion channel–toxin complexes

Acid sensing ion channels (ASICs) are voltage-independent, amiloride-sensitive channels implicated in diverse physiological processes ranging from nociception to taste. Despite the importance of ASICs in physiology, we know little about the mechanism of channel activation. Here we show that psalmoto...

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Detalles Bibliográficos
Autores principales: Baconguis, Isabelle, Gouaux, Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725952/
https://ncbi.nlm.nih.gov/pubmed/22842900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11375
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