The TLR4 Antagonist, Eritoran, Protects Mice from Lethal Influenza Infection

There is pressing need to develop alternatives to annual influenza vaccines and antiviral agents licensed for mitigating influenza infection. Previous studies reported that acute lung injury (ALI) caused by chemical or microbial insults is secondary to generation of host-derived, oxidized phospholip...

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Hlavní autoři: Shirey, Kari Ann, Lai, Wendy, Scott, Alison J., Lipsky, Michael, Mistry, Pragnesh, Pletneva, Lioubov M., Karp, Christopher L., McAlees, Jaclyn, Gioannini, Theresa L., Weiss, Jerrold, Chen, Wilbur H., Ernst, Robert K., Rossignol, Daniel P., Gusovsky, Fabian, Blanco, Jorge C. G., Vogel, Stefanie N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725830/
https://ncbi.nlm.nih.gov/pubmed/23636320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12118
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