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Radioiodination of an endotoxin·MD-2 complex generates a novel sensitive, high affinity ligand for TLR4

A purified complex of metabolically labeled endotoxin ([(3)H] lipooligosaccharide, LOS) and insect-cell derived recombinant human myeloid differentiation factor 2, (MD-2), [(3)H] LOS·MD-2, has been used to demonstrate pM affinity binding interactions with soluble Toll-like receptor 4 ectodomain (TLR...

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Autores principales: Teghanemt, Athmane, Weiss, Jerrold P., Gioannini, Theresa L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779530/
https://ncbi.nlm.nih.gov/pubmed/23439691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425913475688
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