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Isolation of an endotoxin–MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations

Host proinflammatory responses to minute amounts of endotoxins derived from many Gram-negative bacteria require the interaction of lipopolysaccharide-binding protein (LBP), CD14, Toll-like receptor 4 (TLR4) and MD-2. Optimal sensitivity to endotoxin requires an ordered series of endotoxin–protein an...

詳細記述

保存先:
書誌詳細
主要な著者: Gioannini, Theresa L., Teghanemt, Athmane, Zhang, DeSheng, Coussens, Nathan P., Dockstader, Wendie, Ramaswamy, S., Weiss, Jerrold P.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC384716/
https://ncbi.nlm.nih.gov/pubmed/15010525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306906101
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