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Endotoxin·albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of Toll-Like Receptor-4()
Response to Gram-negative bacteria (GNB) is partially mediated by the recognition of GNB-derived endotoxin (E) by host cells. Potent host response to E depends on the sequential interaction of E with lipopolysaccharide binding protein (LBP), CD14, MD-2 and Toll-Like Receptor 4 (TLR4). While CD14 fac...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636710/ https://ncbi.nlm.nih.gov/pubmed/21994253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425911422723 |
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