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At low precursor frequencies the helper T-cell response to chronic self-antigen presentation in vivo is followed by anergy without deletion

The behavior of self-reactive T cells in the peripheral immune system has often been studied by following the fate of adoptively transferred antigen-specific T cells in antigen expressing mice. In most cases, after a period of expansion, such cells undergo a slow clonal deletion, accompanied by the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Steinert, Elizabeth, Schwartz, Ronald H, Singh, Nevil J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725465/
https://ncbi.nlm.nih.gov/pubmed/22806568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242518
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