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At low precursor frequencies the helper T-cell response to chronic self-antigen presentation in vivo is followed by anergy without deletion
The behavior of self-reactive T cells in the peripheral immune system has often been studied by following the fate of adoptively transferred antigen-specific T cells in antigen expressing mice. In most cases, after a period of expansion, such cells undergo a slow clonal deletion, accompanied by the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725465/ https://ncbi.nlm.nih.gov/pubmed/22806568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242518 |
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