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The Strength of Persistent Antigenic Stimulation Modulates Adaptive Tolerance in Peripheral CD4(+) T Cells
The quantitative adaptation of receptor thresholds allows cells to tailor their responses to changes in ambient ligand concentration in many biological systems. Such a cell-intrinsic calibration of T cell receptor (TCR) sensitivity could be involved in regulating responses to autoantigens, but this...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194218/ https://ncbi.nlm.nih.gov/pubmed/14530379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030913 |
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